human LGALS3 shRNA silencing Adenovirus

Name 
Ad-h-LGALS3-shRNA
Cat No 
shADV-213851
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Human LGALS3.

shADV-213851
Ad-h-LGALS3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LGALS3 (galectin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
Description (Vector)
LGALS3 encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
Gene ID
3958
Gene Name (Vector)
galectin 3
Gene Symbol
LGALS3
HGNC ID
HGNC:6563
ORF Size (aa)
753
RefSeq ID
NM_002306
RefSeq Synonyms
NM_002306, NM_001177388, BC068068, BC053667, BC001120,
Species
human
UniGene ID
Hs.531081

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.