human L3MBTL3 shRNA silencing Adenovirus

Name
Ad-h-L3MBTL3-shRNA

Cat No
shADV-213627

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human L3MBTL3.

shADV-213627

Ad-h-L3MBTL3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human L3MBTL3 (l(3)mbt-like 3 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

No

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

H-l(3)mbt-like protein 3; l(3)mbt-like 3; L(3)mbt-like protein 3; lethal(3)malignant brain tumor-like protein 3; MBT1; MBT-1

Description (eCommerce)

L3MBTL3 [Lethal(3)malignant brain tumor-like protein 3] is a putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. L3MBTL3 is required for normal maturation of myeloid progenitor cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/9Q96JM7].

Gene ID

84456

Gene Name (eCommerce)

L3MBTL3, histone methyl-lysine binding protein

Gene Name (Vector)

l(3)mbt-like 3 (Drosophila)

Gene Symbol

L3MBTL3

HGNC ID

HGNC:23035

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2268

ORF Size (bp)

2268 bp

Protein Name (eCommerce)

Lethal(3)malignant brain tumor-like protein 3

RefSeq ID

NM_032438

RefSeq Synonyms

NM_032438, NM_001346551, NM_001346550, NM_001007102, BC060845,

Research Areas

Chromatin Remodeling,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

L3MBTL3 [Lethal(3)malignant brain tumor-like protein 3] is a putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. L3MBTL3 is required for normal maturation of myeloid progenitor cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/9Q96JM7].

UniGene ID

Hs.658051

UniProt ID (eCommerce)

Q96JM7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.