human KRT5 shRNA silencing Adenovirus

Name 
Ad-h-KRT5-shRNA
Cat No 
shADV-213430
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KRT5.

shADV-213430
Ad-h-KRT5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT5 (keratin 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
58 kda cytokeratin;CK5;CK-5;cytokeratin-5;DDD;DDD1;EBS2;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K5;keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types);keratin 5, type II;keratin, type II cytoskeletal 5;Keratin-5;KRT5A;type-II keratin Kb5
Description (eCommerce)
Cytokeratin 5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. [taken from NCBI Entrez Gene (Gene ID: 3852)].
Description (Vector)
KRT5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene ID
3852
Gene Name (eCommerce)
keratin 5
Gene Name (Vector)
keratin 5
Gene Symbol
KRT5
HGNC ID
HGNC:6442
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1773
ORF Size (bp)
1773 bp
Protein Name (eCommerce)
Keratin, type II cytoskeletal 5
RefSeq ID
NM_000424
RefSeq Synonyms
NM_000424, BC071906, BC042132, BC024292,
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
Cytokeratin 5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. [taken from NCBI Entrez Gene (Gene ID: 3852)].
UniGene ID
Hs.433845
UniProt ID (eCommerce)
P13647

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.