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human KRT2 shRNA silencing Adenovirus

Name 
Ad-h-KRT2-shRNA
Cat No 
shADV-213393
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KRT2.

shADV-213393
Ad-h-KRT2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT2 (keratin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CK-2e; K2e; KRT2A; KRT2E; KRTE
Description (Vector)
KRT2 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene ID
3849
Gene Name (Vector)
keratin 2
Gene Symbol
KRT2
HGNC ID
HGNC:6439
ORF Size (aa)
1920
ORF Size (bp)
1920 bp
RefSeq ID
NM_000423
RefSeq Synonyms
NM_000423, BC099644, BC099643, BC096294,
Species
human
UniGene ID
Hs.707

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.