human KRT19 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KRT19.
shADV-213388
Ad-h-KRT19-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT19 (keratin 19). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
40-kDa keratin intermediate filament; CK19; CK-19; cytokeratin 19; Cytokeratin-19; K19; K1CS; keratin 19, type I; keratin, type I cytoskeletal 19; keratin, type I, 40-kd; Keratin-19
Description (eCommerce)
Cytokeratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. Cytokeratin 19 is Involved in the organization of myofibers. Together with Cytokeratin 8, it helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08727].
Description (Vector)
KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Gene ID
3880
Gene Name (eCommerce)
keratin 19
Gene Name (Vector)
keratin 19
Gene Symbol
KRT19
HGNC ID
HGNC:6436
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1203
ORF Size (bp)
1203 bp
Protein Name (eCommerce)
Keratin, type I cytoskeletal 19
RefSeq ID
NM_002276
RefSeq Synonyms
NM_002276, BC084574, BC067744, BC010409, BC007628, BC002539,
Research Areas
Cytoskeleton,Estrogen Signaling,Host-Virus Interactions,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,infectious_disease
Species
human
Target Sentence
Cytokeratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. Cytokeratin 19 is Involved in the organization of myofibers. Together with Cytokeratin 8, it helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08727].
UniGene ID
Hs.654568
UniProt ID (eCommerce)
P08727
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.