human KRT18 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KRT18.
shADV-213382
Ad-h-KRT18-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT18 (keratin 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cell proliferation-inducing gene 46 protein; CK18; CK-18; CYK18; cytokeratin 18; Cytokeratin-18; K18; keratin 18, type I; keratin, type I cytoskeletal 18; Keratin-18
Description (eCommerce)
Cytokeratin 18 is a type I intermediate filament. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. [taken from NCBI Entrez Gene (Gene ID: 3875)].
Description (Vector)
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
3875
Gene Name (eCommerce)
keratin 18
Gene Name (Vector)
keratin 18
Gene Symbol
KRT18
HGNC ID
HGNC:6430
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1293
ORF Size (bp)
1293 bp
Protein Name (eCommerce)
Keratin, type I cytoskeletal 18
RefSeq ID
NM_000224
RefSeq Synonyms
NM_199187, NM_000224, BC072017, BC020982, BC008636, BC004253, BC000698, BC000180,
Research Areas
Apoptosis,Cancer,Cell Cycle,EGFR Signaling,Golgi Apparatus,Host-Virus Interactions,Signal Transduction
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,infectious_disease,signal_transduction
Species
human
Target Sentence
Cytokeratin 18 is a type I intermediate filament. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. [taken from NCBI Entrez Gene (Gene ID: 3875)].
UniGene ID
Hs.406013
UniProt ID (eCommerce)
P05783
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.