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human KRT16 shRNA silencing Adenovirus

Name 
Ad-h-KRT16-shRNA
Cat No 
shADV-213381
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KRT16.

shADV-213381
Ad-h-KRT16-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT16 (keratin 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CK-16; CK16; Cytokeratin-16; FNEPPK; K16; K1CP; KRT16A; Keratin-16; NEPPK; PC1; cytokeratin 16; focal non-epidermolytic palmoplantar keratoderma; keratin 16, type I; keratin, type I cytoskeletal 16
Description (Vector)
KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
Gene ID
3868
Gene Name (eCommerce)
keratin 16
Gene Name (Vector)
keratin 16
Gene Symbol
KRT16
HGNC ID
HGNC:6423
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
Protein Name (eCommerce)
Keratin, type I cytoskeletal 16
RefSeq ID
NM_005557
RefSeq Synonyms
NM_005557, BC039169,
Research Areas
Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
UniGene ID
Hs.655160
UniProt ID (eCommerce)
P08779

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.