human KPNA5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KPNA5.
shADV-213348
Ad-h-KPNA5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KPNA5 (karyopherin subunit alpha 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IPOA6; SRP6
Description (Vector)
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus.
Gene ID
3841
Gene Name (Vector)
karyopherin subunit alpha 5
Gene Symbol
KPNA5
HGNC ID
HGNC:6398
ORF Size (aa)
1620
ORF Size (bp)
1620 bp
RefSeq ID
NM_002269
RefSeq Synonyms
NM_002269, BC047409,
Species
human
UniGene ID
Hs.182971
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.