human KLK6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KLK6.
shADV-213302
Ad-h-KLK6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KLK6 (kallikrein related peptidase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Bssp; hK6; Klk7; PRSS18; PRSS9; SP59
Description (Vector)
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Gene ID
5653
Gene Name (Vector)
kallikrein related peptidase 6
Gene Symbol
KLK6
HGNC ID
HGNC:6367
ORF Size (aa)
735
RefSeq ID
NM_002774
RefSeq Synonyms
NM_002774, NM_001319949, NM_001319948, NM_001012965, NM_001012964, BC015525,
Species
human
UniGene ID
Hs.79361
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.