human KIAA1949 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PPP1R18.
shADV-213053
Ad-h-KIAA1949-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PPP1R18 (protein phosphatase 1 regulatory subunit 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HKMT1098; KIAA1949; phostensin; protein phosphatase 1 F-actin cytoskeleton targeting subunit; Protein phosphatase 1 F-actin cytoskeleton-targeting subunit; Protein phosphatase 1 regulatory subunit 18
Description (eCommerce)
PPP1R18 may target protein phosphatase 1 to F-actin cytoskeleton [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6NYC8].
Description (Vector)
Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 (PubMed 17374523)).(supplied by OMIM, Mar 2008)
Gene ID
170954
Gene Name (eCommerce)
protein phosphatase 1 regulatory subunit 18
Gene Name (Vector)
protein phosphatase 1 regulatory subunit 18
Gene Symbol
PPP1R18
HGNC ID
HGNC:29413
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1842
ORF Size (bp)
1842 bp
Protein Name (eCommerce)
Phostensin
RefSeq ID
NM_001134870
RefSeq Synonyms
NM_133471, NM_001134870, BC066644,
Research Areas
Cytoskeleton,Kinase/Phosphatase
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
PPP1R18 may target protein phosphatase 1 to F-actin cytoskeleton [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6NYC8].
UniGene ID
Hs.696054
UniProt ID (eCommerce)
Q6NYC8
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.