human KIAA1219 shRNA silencing Adenovirus

Name
Ad-h-KIAA1219-shRNA

Cat No
shADV-212985

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RALGAPB.

shADV-212985

Ad-h-KIAA1219-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RALGAPB (Ral GTPase activating protein non-catalytic beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

KIAA1219; p170; Ral GTPase activating protein, beta subunit (non-catalytic); ral GTPase-activating protein subunit beta; RalGAPbeta

Description (eCommerce)

Ral GTPase-activating protein subunit beta (RALGAPB) is the non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALBÂ [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86X10].

Gene ID

57148

Gene Name (eCommerce)

Ral GTPase activating protein non-catalytic beta subunit

Gene Name (Vector)

Ral GTPase activating protein non-catalytic beta subunit

Gene Symbol

RALGAPB

HGNC ID

HGNC:29221

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4485

ORF Size (bp)

4485 bp

Protein Name (eCommerce)

Ral GTPase-activating protein subunit beta

RefSeq ID

NM_020336

RefSeq Synonyms

NM_020336, NM_001282918, NM_001282917, BC047482,

Research Areas

Cell Biology

Research Areas (Faceted)

cell_biology

Species

human

Target Sentence

Ral GTPase-activating protein subunit beta (RALGAPB) is the non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALBÂ [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86X10].

UniGene ID

Hs.655758

UniProt ID (eCommerce)

Q86X10

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.