human KIAA0467 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SZT2.
shADV-212919
Ad-h-KIAA0467-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SZT2 (seizure threshold 2 homolog (mouse)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C1orf84; EIEE18; KIAA0467; SZT2A; SZT2B
Description (Vector)
SZT2 is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis.
Gene ID
23334
Gene Name (Vector)
seizure threshold 2 homolog (mouse)
Gene Symbol
SZT2
HGNC ID
HGNC:29040
ORF Size (aa)
7602
ORF Size (bp)
7602 bp
RefSeq ID
NM_015284
RefSeq Synonyms
NM_015284, BC151232,
Species
human
UniGene ID
Hs.643560
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.