human KHSRP shRNA silencing Adenovirus

Name 
Ad-h-KHSRP-shRNA
Cat No 
shADV-212878
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KHSRP.

shADV-212878
Ad-h-KHSRP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KHSRP (KH-type splicing regulatory protein). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; far upstream element-binding protein 2; FBP2; FUBP2; FUSE-binding protein 2; KH type-splicing regulatory protein; KSRP; p75
Description (eCommerce)
KH-type splicing regulatory protein (KSRP) contains four K homology RNA-binding domains. KH domains are found in a wide variety of proteins including ribosomal proteins, transcription factors, and mRNA processing proteins. KSRP has been found to promote the degradation of mRNAs that encode proteins involved in proliferation and the inflammatory response.
Description (Vector)
The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 (PubMed 9136930); Gherzi et al., 2004 (PubMed 15175153)).(supplied by OMIM, Apr 2010)
Gene ID
8570
Gene Name (eCommerce)
KH-type splicing regulatory protein
Gene Name (Vector)
KH-type splicing regulatory protein
Gene Symbol
KHSRP
HGNC ID
HGNC:6316
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2133
ORF Size (bp)
2133 bp
Protein Name (eCommerce)
Far upstream element-binding protein 2
RefSeq ID
NM_003685
RefSeq Synonyms
NM_003685, BC085004,
Research Areas
Gene Expression,mRNA Binding,mRNA Processing,mRNA Splicing,mRNA transport,RNA Binding,RNA Processing,RNA Transport,Transcription Factor/Regulator,Transport
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
KH-type splicing regulatory protein (KSRP) contains four K homology RNA-binding domains. KH domains are found in a wide variety of proteins including ribosomal proteins, transcription factors, and mRNA processing proteins. KSRP has been found to promote the degradation of mRNAs that encode proteins involved in proliferation and the inflammatory response.
UniGene ID
Hs.708128
UniProt ID (eCommerce)
Q92945

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.