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human KDM3A shRNA silencing Adenovirus

Name 
Ad-h-KDM3A-shRNA
Cat No 
shADV-212839
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KDM3A.

shADV-212839
Ad-h-KDM3A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KDM3A (lysine demethylase 3A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
JHDM2A; JHMD2A; jmjC domain-containing histone demethylation protein 2A; JMJD1; JMJD1A; jumonji C domain-containing histone demethylase 2A; jumonji domain-containing protein 1A; lysine (K)-specific demethylase 3A; lysine-specific demethylase 3A; testis-specific protein A; TSGA
Description (eCommerce)
JMJD1A/JHDM2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in the regulation of chromatin dynamics and influences transcriptional activation and suppression. JMJD1A/JHDM2A specifically demethylates mono- and dimethyl-histone 3 lysine 9. Demethylation of histones by JMJD1A has been shown to facilitate transcriptional activation by the androgen receptor and promote transcription of smooth muscle cell differentiation marker.
Description (Vector)
KDM3A encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants.
Gene ID
55818
Gene Name (eCommerce)
lysine demethylase 3A
Gene Name (Vector)
lysine demethylase 3A
Gene Symbol
KDM3A
HGNC ID
HGNC:20815
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3963
ORF Size (bp)
3963 bp
Protein Name (eCommerce)
Lysine-specific demethylase 3A
RefSeq ID
NM_018433
RefSeq Synonyms
NM_018433, NM_001146688, BC172547, BC156518,
Research Areas
Cancer,Chromatin Remodeling,Histone Modification,Spermatogenesis,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
JMJD1A/JHDM2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in the regulation of chromatin dynamics and influences transcriptional activation and suppression. JMJD1A/JHDM2A specifically demethylates mono- and dimethyl-histone 3 lysine 9. Demethylation of histones by JMJD1A has been shown to facilitate transcriptional activation by the androgen receptor and promote transcription of smooth muscle cell differentiation marker.
UniGene ID
Hs.557425
UniProt ID (eCommerce)
Q9Y4C1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.