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human KDM2B shRNA silencing Adenovirus

Name 
Ad-h-KDM2B-shRNA
Cat No 
shADV-212837
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human KDM2B.

shADV-212837
Ad-h-KDM2B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KDM2B (lysine demethylase 2B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CXXC2; Fbl10; FBXL10; JHDM1B; PCCX2
Description (Vector)
KDM2B encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Gene ID
84678
Gene Name (Vector)
lysine demethylase 2B
Gene Symbol
KDM2B
HGNC ID
HGNC:13610
ORF Size (aa)
2121
ORF Size (bp)
2121 bp
RefSeq ID
NM_001005366
RefSeq Synonyms
NM_032590, NM_001005366, BC115380,
Species
human
UniGene ID
Hs.524800

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.