human KCNMB1 shRNA silencing Adenovirus

Name
Ad-h-KCNMB1-shRNA

Cat No
shADV-212760

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human KCNMB1.

shADV-212760

Ad-h-KCNMB1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BKbeta1; hbeta1; hslo-beta; K(VCA)beta; k(VCA)beta-1; SLO-BETA; slo-beta-1

Description (Vector)

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.

Gene ID

3779

Gene Name (Vector)

potassium calcium-activated channel subfamily M regulatory beta subunit 1

Gene Symbol

KCNMB1

HGNC ID

HGNC:6285

ORF Size (aa)

393

RefSeq ID

NM_004137

RefSeq Synonyms

NM_004137, BC025707,

Species

human

UniGene ID

Hs.484099

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.