human KCNK2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KCNK2.
shADV-212742
Ad-h-KCNK2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KCNK2 (potassium two pore domain channel subfamily K member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hTREK-1c; hTREK-1e; K2p2.1; TPKC1; TREK; TREK-1; TREK1
Description (Vector)
KCNK2 encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
3776
Gene Name (Vector)
potassium two pore domain channel subfamily K member 2
Gene Symbol
KCNK2
HGNC ID
HGNC:6277
ORF Size (aa)
1236
ORF Size (bp)
1236 bp
RefSeq ID
NM_014217
RefSeq Synonyms
NM_014217, NM_001017425, NM_001017424, BC143586, BC101695, BC101693, BC069462,
Species
human
UniGene ID
Hs.497745
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.