human LDHA Over-expression AAV

Name 
AAV-h-LDHA
Cat No 
AAV-213785
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LDHA.

AAV-213785
AAV-h-LDHA

Ready-to-use AAV expressing Human LDHA (lactate dehydrogenase A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GSD11; HEL-S-133P; LDHM; PIG19
Description (Vector)
LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
Gene ID
3939
Gene Name (Vector)
lactate dehydrogenase A
Gene Symbol
LDHA
HGNC ID
HGNC:6535
ORF Size (aa)
999
ORF Size (bp)
999 bp
RefSeq ID
NM_005566
RefSeq Synonyms
NM_005566, NM_001165416, NM_001165415, NM_001165414, NM_001135239, BC067223,
Species
human
UniGene ID
Hs.2795

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.