human INA shRNA silencing Adenovirus

Name 
Ad-h-INA-shRNA
Cat No 
shADV-212253
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human INA.

shADV-212253
Ad-h-INA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human INA (internexin neuronal intermediate filament protein alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
66 kDa neurofilament protein; alpha-internexin; alpha-Inx; NEF5; Neurofilament 5; neurofilament 5 (66kD); Neurofilament-66; neurofilament-66, tax-binding protein; NF-66; TXBP-1
Description (eCommerce)
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites.INA is a member of the intermediate filament family and is involved in the morphogenesis of neurons [taken from NCBI Entrez Gene (Gene ID: 9118)].
Description (Vector)
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.
Gene ID
9118
Gene Name (eCommerce)
internexin neuronal intermediate filament protein alpha
Gene Name (Vector)
internexin neuronal intermediate filament protein alpha
Gene Symbol
INA
HGNC ID
HGNC:6057
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1500
ORF Size (bp)
1500 bp
Protein Name (eCommerce)
Alpha-internexin
RefSeq ID
NM_032727
RefSeq Synonyms
NM_032727, BC006359,
Research Areas
Cytoskeleton,Neurobiology,Neurodevelopment,Neurogenesis
Research Areas (Faceted)
cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites.INA is a member of the intermediate filament family and is involved in the morphogenesis of neurons [taken from NCBI Entrez Gene (Gene ID: 9118)].
UniGene ID
Hs.500916
UniProt ID (eCommerce)
Q16352

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.