human IKZF3 shRNA silencing Adenovirus

Name 
Ad-h-IKZF3-shRNA
Cat No 
shADV-212019
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human IKZF3.

shADV-212019
Ad-h-IKZF3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IKZF3 (IKAROS family zinc finger 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AIO; AIOLOS; ZNFN1A3
Description (Vector)
IKZF3 encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. IKZF3 product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Gene ID
22806
Gene Name (Vector)
IKAROS family zinc finger 3
Gene Symbol
IKZF3
HGNC ID
HGNC:13178
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_012481
RefSeq Synonyms
NM_183232, NM_183231, NM_183230, NM_183229, NM_183228, NM_012481, NM_001284516, NM_001284515, NM_001284514, NM_001257414, NM_001257413, NM_001257412, NM_001257411, NM_001257410, NM_001257409, NM_001257408, BC032707,
Species
human
UniGene ID
Hs.444388

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.