human IGF2BP1 shRNA silencing Adenovirus

Name 
Ad-h-IGF2BP1-shRNA
Cat No 
shADV-211919
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human IGF2BP1.

shADV-211919
Ad-h-IGF2BP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
coding region determinant-binding protein; CRDBP; CRD-BP; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; IMP1; IMP-1; insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP; insulin-like growth factor 2 mRNA-binding protein 1; VICKZ family member 1; VICKZ1; ZBP1; ZBP-1; zipcode-binding protein 1
Description (eCommerce)
Insulin-like growth factor 2 mRNA binding protein 1 (IMP1) is a member of the insulin-like growth factor 2 mRNA-binding protein family. IMP1 contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation [taken from NCBI Entrez Gene (Gene ID: 10642)].
Description (Vector)
IGF2BP1 encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
10642
Gene Name (eCommerce)
insulin like growth factor 2 mRNA binding protein 1
Gene Name (Vector)
insulin like growth factor 2 mRNA binding protein 1
Gene Symbol
IGF2BP1
HGNC ID
HGNC:28866
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1734
ORF Size (bp)
1734 bp
Protein Name (eCommerce)
Insulin-like growth factor 2 mRNA-binding protein 1
RefSeq ID
NM_006546
RefSeq Synonyms
NM_006546, NM_001160423, BC156957, BC152770,
Research Areas
BDNF Signaling,Cancer,Gene Expression,Immunology,MicroRNAs in Cancer,mRNA Binding,mRNA transport,Neurobiology,RNA Binding,RNA Processing,RNA Transport,Translational Control
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Insulin-like growth factor 2 mRNA binding protein 1 (IMP1) is a member of the insulin-like growth factor 2 mRNA-binding protein family. IMP1 contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation [taken from NCBI Entrez Gene (Gene ID: 10642)].
UniGene ID
Hs.144936
UniProt ID (eCommerce)
Q9NZI8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.