human IFIH1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human IFIH1.
shADV-211802
Ad-h-IFIH1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human IFIH1 (interferon induced with helicase C domain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGS7; Hlcd; IDDM19; MDA-5; MDA5; RLR-2; SGMRT1
Description (Vector)
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
Gene ID
64135
Gene Name (Vector)
interferon induced with helicase C domain 1
Gene Symbol
IFIH1
HGNC ID
HGNC:18873
ORF Size (aa)
3078
ORF Size (bp)
3078 bp
RefSeq ID
NM_022168
RefSeq Synonyms
NM_022168, BC111750, BC046208,
Species
human
UniGene ID
Hs.163173
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.