human IFI16 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human IFI16.
shADV-211792
Ad-h-IFI16-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human IFI16 (interferon gamma inducible protein 16). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IFNGIP1; PYHIN2
Description (Vector)
IFI16 encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3428
Gene Name (Vector)
interferon gamma inducible protein 16
Gene Symbol
IFI16
HGNC ID
HGNC:5395
ORF Size (aa)
2190
ORF Size (bp)
2190 bp
RefSeq ID
NM_005531
RefSeq Synonyms
NM_005531, NM_001206567, BC017059,
Species
human
UniGene ID
Hs.380250
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.