human ICAM5 shRNA silencing Adenovirus

Name 
Ad-h-ICAM5-shRNA
Cat No 
shADV-211752
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ICAM5.

shADV-211752
Ad-h-ICAM5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ICAM5 (intercellular adhesion molecule 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ICAM-5; intercellular adhesion molecule 5; intercellular adhesion molecule 5, telencephalin; telencephalin; TLCN; TLN
Description (eCommerce)
ICAM5, also known as telencepahlin, is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. ICAM5 is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases [taken from NCBI Entrez Gene (Gene ID: 7087)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UMF0].
Description (Vector)
ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Gene ID
7087
Gene Name (eCommerce)
intercellular adhesion molecule 5
Gene Name (Vector)
intercellular adhesion molecule 5
Gene Symbol
ICAM5
HGNC ID
HGNC:5348
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2775
ORF Size (bp)
2775 bp
Protein Name (eCommerce)
Intercellular adhesion molecule 5
RefSeq ID
NM_003259
RefSeq Synonyms
NM_003259, BC026338,
Research Areas
Immunology,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology,neurobiology
Species
human
Target Sentence
ICAM5, also known as telencepahlin, is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. ICAM5 is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases [taken from NCBI Entrez Gene (Gene ID: 7087)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UMF0].
UniGene ID
Hs.465862
UniProt ID (eCommerce)
Q9UMF0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.