human ICA1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ICA1.
shADV-211745
Ad-h-ICA1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ICA1 (islet cell autoantigen 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ICA69; ICAp69
Description (Vector)
ICA1 encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Gene ID
3382
Gene Name (Vector)
islet cell autoantigen 1
Gene Symbol
ICA1
HGNC ID
HGNC:5343
ORF Size (aa)
1449
ORF Size (bp)
1449 bp
RefSeq ID
NM_004968
RefSeq Synonyms
NM_022307, NM_004968, NM_001276478, NM_001136020, BC008640,
Species
human
UniGene ID
Hs.487561
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.