human HTR6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HTR6.
shADV-211709
Ad-h-HTR6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HTR6 (5-hydroxytryptamine receptor 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5-HT6; 5-HT-6; 5-HT6R; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; 5-hydroxytryptamine receptor 6; serotonin receptor 6
Description (eCommerce)
5-HT6 is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P50406].
Gene ID
3362
Gene Name (eCommerce)
5-hydroxytryptamine receptor 6
Gene Name (Vector)
5-hydroxytryptamine receptor 6
Gene Symbol
HTR6
HGNC ID
HGNC:5301
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1323
ORF Size (bp)
1323 bp
Protein Name (eCommerce)
5-hydroxytryptamine receptor 6
RefSeq ID
NM_000871
RefSeq Synonyms
NM_000871, BC074996, BC074995,
Research Areas
GPCR Signaling,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,neurobiology
Species
human
Target Sentence
5-HT6 is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P50406].
UniGene ID
Hs.22180
UniProt ID (eCommerce)
P50406
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.