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human HTR1B shRNA silencing Adenovirus

Name 
Ad-h-HTR1B-shRNA
Cat No 
shADV-211685
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HTR1B.

shADV-211685
Ad-h-HTR1B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HTR1B (5-hydroxytryptamine receptor 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
5-HT-1B; 5-HT-1D-beta; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12
Description (Vector)
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 (PubMed 1359584)). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.(supplied by OMIM, Oct 2009)
Gene ID
3351
Gene Name (Vector)
5-hydroxytryptamine receptor 1B
Gene Symbol
HTR1B
HGNC ID
HGNC:5287
ORF Size (aa)
1173
RefSeq ID
NM_000863
RefSeq Synonyms
NM_000863, BC096207, BC069065,
Species
human
UniGene ID
Hs.123016

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.