human HPR shRNA silencing Adenovirus

Name 
Ad-h-HPR-shRNA
Cat No 
shADV-211500
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HPR.

shADV-211500
Ad-h-HPR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HPR (haptoglobin-related protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
A-259H10.2; HP
Description (Vector)
HPR encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
Gene ID
3250
Gene Name (Vector)
haptoglobin-related protein
Gene Symbol
HPR
HGNC ID
HGNC:5156
ORF Size (aa)
1047
ORF Size (bp)
1047 bp
RefSeq ID
NM_020995
RefSeq Synonyms
NM_020995, BC160066,
Species
human
UniGene ID
Hs.655361

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.