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human HOXD11 shRNA silencing Adenovirus

Name 
Ad-h-HOXD11-shRNA
Cat No 
shADV-211473
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HOXD11.

shADV-211473
Ad-h-HOXD11-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HOXD11 (homeobox D11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HOX4; HOX4F
Description (Vector)
HOXD11 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD11 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.
Gene ID
3237
Gene Name (Vector)
homeobox D11
Gene Symbol
HOXD11
HGNC ID
HGNC:5134
ORF Size (aa)
1017
ORF Size (bp)
1017 bp
RefSeq ID
NM_021192
RefSeq Synonyms
NM_021192, BC160135,
Species
human
UniGene ID
Hs.421136

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.