human HNRNPH3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HNRNPH3.
shADV-211380
Ad-h-HNRNPH3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HNRNPH3 (heterogeneous nuclear ribonucleoprotein H3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2H9; HNRPH3
Description (Vector)
HNRNPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized.
Gene ID
3189
Gene Name (Vector)
heterogeneous nuclear ribonucleoprotein H3
Gene Symbol
HNRNPH3
HGNC ID
HGNC:5043
ORF Size (aa)
996
ORF Size (bp)
996 bp
RefSeq ID
NM_012207
RefSeq Synonyms
NM_021644, NM_012207, NM_001322453, NM_001322452, NM_001322451, NM_001322450, NM_001322449, NM_001322448, NM_001322447, NM_001322446, NM_001322445, NM_001322444, NM_001322443, NM_001322442, NM_001322441, NM_001322440, NM_001322439, NM_001322438, NM_001322437, NM_001322436, NM_001322434, BC039824,
Species
human
UniGene ID
Hs.643472
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.