human HMGA2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HMGA2.
shADV-211266
Ad-h-HMGA2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HMGA2 (high mobility group AT-hook 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BABL; HMGI-C; HMGIC; LIPO; STQTL9
Description (Vector)
HMGA2 encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
8091
Gene Name (Vector)
high mobility group AT-hook 2
Gene Symbol
HMGA2
HGNC ID
HGNC:5009
ORF Size (aa)
330
RefSeq ID
NM_003483
RefSeq Synonyms
NM_003484, NM_003483, NM_001330190, NM_001300919, NM_001300918, BC160115,
Species
human
UniGene ID
Hs.505924
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.