human HLX shRNA silencing Adenovirus

Name
Ad-h-HLX-shRNA

Cat No
shADV-211245

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human HLX.

shADV-211245

Ad-h-HLX-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HLX (H2.0 like homeobox). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

53

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

H2.0-like homeo box-1; H2.0-like homeobox 1; H2.0-like homeobox protein; HB24; HLX1; homeobox protein HB24; homeobox protein HLX1

Description (eCommerce)

H2.0-like homeobox protein (HLX) is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. HLX is involved in embryogenesis and hematopoiesis (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q14774].

Gene ID

3142

Gene Name (eCommerce)

H2.0 like homeobox

Gene Name (Vector)

H2.0 like homeobox

Gene Symbol

HLX

HGNC ID

HGNC:4978

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1467

ORF Size (bp)

1467 bp

Protein Name (eCommerce)

H2.0-like homeobox protein

RefSeq ID

NM_021958

RefSeq Synonyms

NM_021958, BC033808, BC007294,

Research Areas

Interleukin Signaling,Neurobiology,Neurodevelopment,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,developmental_biology,immunology,neurobiology,signal_transduction,transcription_translation

Species

human

Target Sentence

H2.0-like homeobox protein (HLX) is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. HLX is involved in embryogenesis and hematopoiesis (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q14774].

UniGene ID

Hs.74870

UniProt ID (eCommerce)

Q14774

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.