human HIST1H3B shRNA silencing Adenovirus

Name 
Ad-h-HIST1H3B-shRNA
Cat No 
shADV-211123
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human HIST1H3B.

shADV-211123
Ad-h-HIST1H3B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HIST1H3B (histone cluster 1 H3 family member b). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
H3/l; H3FL
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Gene ID
8358
Gene Name (Vector)
histone cluster 1 H3 family member b
Gene Symbol
HIST1H3B
HGNC ID
HGNC:4776
ORF Size (aa)
411
RefSeq ID
NM_003537
RefSeq Synonyms
NM_003537, BC099630, BC096134, BC096133, BC096132, BC069133,
Species
human
UniGene ID
Hs.533292

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.