human HERC5 shRNA silencing Adenovirus

Name 
Ad-h-HERC5-shRNA
Cat No 
shADV-210954
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HERC5.

shADV-210954
Ad-h-HERC5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CEB1; CEBP1
Description (Vector)
HERC5 is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Gene ID
51191
Gene Name (Vector)
HECT and RLD domain containing E3 ubiquitin protein ligase 5
Gene Symbol
HERC5
HGNC ID
HGNC:24368
ORF Size (aa)
3075
ORF Size (bp)
3075 bp
RefSeq ID
NM_016323
RefSeq Synonyms
NM_016323, BC140716,
Species
human
UniGene ID
Hs.26663

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.