human H2AFZ shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human H2AFZ.
shADV-210748
Ad-h-H2AFZ-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human H2AFZ (H2A histone family member Z). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H2A.z; H2A.Z-1; H2A/z; H2AZ
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Gene ID
3015
Gene Name (Vector)
H2A histone family member Z
Gene Symbol
H2AFZ
HGNC ID
HGNC:4741
ORF Size (aa)
387
RefSeq ID
NM_002106
RefSeq Synonyms
NM_002106, BC103743, BC020936, BC018002,
Species
human
UniGene ID
Hs.119192
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.