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human H2AFY shRNA silencing Adenovirus

Name 
Ad-h-H2AFY-shRNA
Cat No 
shADV-210745
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human H2AFY.

shADV-210745
Ad-h-H2AFY-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human H2AFY (H2A histone family member Y). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
H2A.y; H2A/y; H2AF12M; MACROH2A1.1; macroH2A1.2; mH2A1
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
9555
Gene Name (Vector)
H2A histone family member Y
Gene Symbol
H2AFY
HGNC ID
HGNC:4740
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_138610
RefSeq Synonyms
NM_138610, NM_138609, NM_004893, NM_001040158, BC095406, BC013331,
Species
human
UniGene ID
Hs.599225

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.