human GRSF1 shRNA silencing Adenovirus

Name 
Ad-h-GRSF1-shRNA
Cat No 
shADV-210566
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GRSF1.

shADV-210566
Ad-h-GRSF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GRSF1 (G-rich RNA sequence binding factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
G-rich sequence factor 1; GRSF-1
Description (eCommerce)
The protein G-rich sequence factor 1 is encoded by the gene GRSF1. G-rich sequence factor 1 is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro [taken from NCBI Entrez Gene (Gene ID: 2926)].
Description (Vector)
GRSF1 is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
2926
Gene Name (eCommerce)
G-rich RNA sequence binding factor 1
Gene Name (Vector)
G-rich RNA sequence binding factor 1
Gene Symbol
GRSF1
HGNC ID
HGNC:4610
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1308
ORF Size (bp)
1308 bp
Protein Name (eCommerce)
G-rich sequence factor 1
RefSeq ID
NM_002092
RefSeq Synonyms
NM_002092, NM_001098477, BC040485,
Research Areas
Host-Virus Interactions,Mitochondrion,mRNA Binding,mRNA Processing,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,transcription_translation
Species
human
Target Sentence
The protein G-rich sequence factor 1 is encoded by the gene GRSF1. G-rich sequence factor 1 is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro [taken from NCBI Entrez Gene (Gene ID: 2926)].
UniGene ID
Hs.309763
UniProt ID (eCommerce)
Q12849

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.