human L3MBTL3 Over-expression AAV

Name
AAV-h-L3MBTL3

Cat No
AAV-213627

Availability
4-5 weeks

This is an AAV expressing Human L3MBTL3.

AAV-213627

AAV-h-L3MBTL3

Ready-to-use AAV expressing Human L3MBTL3 (l(3)mbt-like 3 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

H-l(3)mbt-like protein 3; l(3)mbt-like 3; L(3)mbt-like protein 3; lethal(3)malignant brain tumor-like protein 3; MBT1; MBT-1

Description (eCommerce)

L3MBTL3 [Lethal(3)malignant brain tumor-like protein 3] is a putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. L3MBTL3 is required for normal maturation of myeloid progenitor cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/9Q96JM7].

Gene ID

84456

Gene Name (eCommerce)

L3MBTL3, histone methyl-lysine binding protein

Gene Name (Vector)

l(3)mbt-like 3 (Drosophila)

Gene Symbol

L3MBTL3

HGNC ID

HGNC:23035

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2268

ORF Size (bp)

2268 bp

Protein Name (eCommerce)

Lethal(3)malignant brain tumor-like protein 3

RefSeq ID

NM_032438

RefSeq Synonyms

NM_032438, NM_001346551, NM_001346550, NM_001007102, BC060845,

Research Areas

Chromatin Remodeling,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

L3MBTL3 [Lethal(3)malignant brain tumor-like protein 3] is a putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. L3MBTL3 is required for normal maturation of myeloid progenitor cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/9Q96JM7].

UniGene ID

Hs.658051

UniProt ID (eCommerce)

Q96JM7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.