human GPR172A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SLC52A2.
shADV-210319
Ad-h-GPR172A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SLC52A2 (solute carrier family 52 member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BVVLS2; D15Ertd747e; GPCR41; GPR172A; hRFT3; PAR1; RFT3; RFVT2
Description (Vector)
SLC52A2 encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
Gene ID
79581
Gene Name (Vector)
solute carrier family 52 member 2
Gene Symbol
SLC52A2
HGNC ID
HGNC:30224
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
RefSeq ID
NM_024531
RefSeq Synonyms
NM_024531, NM_001253816, NM_001253815, BC002917,
Species
human
UniGene ID
Hs.6459
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.