human GPER shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GPER1.
shADV-210227
Ad-h-GPER-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GPER1 (G protein-coupled estrogen receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPER; GPR30; LERGU; LERGU2; LyGPR; mER
Description (Vector)
GPER is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Gene ID
2852
Gene Name (Vector)
G protein-coupled estrogen receptor 1
Gene Symbol
GPER1
HGNC ID
HGNC:4485
ORF Size (aa)
1224
ORF Size (bp)
1224 bp
RefSeq ID
NM_001505
RefSeq Synonyms
NM_001505, NM_001098201, NM_001039966, BC082766, BC011634,
Species
human
UniGene ID
Hs.20961
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.