human GJB2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GJB2.
shADV-209923
Ad-h-GJB2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GJB2 (gap junction protein beta 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CX26; DFNA3; DFNA3A; DFNB1; DFNB1A; HID; KID; NSRD1; PPK
Description (Vector)
GJB2 encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.
Gene ID
2706
Gene Name (Vector)
gap junction protein beta 2
Gene Symbol
GJB2
HGNC ID
HGNC:4284
ORF Size (aa)
681
ORF Size (bp)
681 bp
RefSeq ID
NM_004004
RefSeq Synonyms
NM_004004, BC071703, BC017048,
Species
human
UniGene ID
Hs.714494
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.