human GCLM shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GCLM.
shADV-209746
Ad-h-GCLM-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GCLM (glutamate-cysteine ligase modifier subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GLCLR
Description (Vector)
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
Gene ID
2730
Gene Name (Vector)
glutamate-cysteine ligase modifier subunit
Gene Symbol
GCLM
HGNC ID
HGNC:4312
ORF Size (aa)
825
ORF Size (bp)
825 bp
RefSeq ID
NM_002061
RefSeq Synonyms
NM_002061, NM_001308253, BC041809,
Species
human
UniGene ID
Hs.315562
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.