human GCKR shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GCKR.
shADV-209743
Ad-h-GCKR-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GCKR (glucokinase regulator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FGQTL5; GKRP
Description (Vector)
GCKR encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Gene ID
2646
Gene Name (Vector)
glucokinase regulator
Gene Symbol
GCKR
HGNC ID
HGNC:4196
ORF Size (aa)
1878
ORF Size (bp)
1878 bp
RefSeq ID
NM_001486
RefSeq Synonyms
NM_001486, BC130483, BC130481,
Species
human
UniGene ID
Hs.89771
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.