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human GBA2 shRNA silencing Adenovirus

Name 
Ad-h-GBA2-shRNA
Cat No 
shADV-209701
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human GBA2.

shADV-209701
Ad-h-GBA2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GBA2 (glucosylceramidase beta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AD035; NLGase; SPG46
Description (Vector)
GBA2 encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.
Gene ID
57704
Gene Name (Vector)
glucosylceramidase beta 2
Gene Symbol
GBA2
HGNC ID
HGNC:18986
ORF Size (aa)
2784
ORF Size (bp)
2784 bp
RefSeq ID
NM_020944
RefSeq Synonyms
NM_020944, NM_001330660, BC011363,
Species
human
UniGene ID
Hs.443134

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.