human GATAD2B shRNA silencing Adenovirus

Name 
Ad-h-GATAD2B-shRNA
Cat No 
shADV-209687
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GATAD2B.

shADV-209687
Ad-h-GATAD2B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GATAD2B (GATA zinc finger domain containing 2B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GATA zinc finger domain-containing protein 2B; MRD18; p66/p68; P66beta; p68; transcription repressor p66 beta component of the MeCP1 complex; transcriptional repressor p66-beta
Description (eCommerce)
P66beta/GATAD2B interacts with MBD2 (methyl-CpG-binding domain 2) and MBD3 (methyl-CpG-binding domain 3) and participates in transcriptional repression in association with the MBD2/NuRD and MBD3/NuRD histone deacetylase complexes. P66beta/GATAD2B is SUMOylated in vivo and its repressive activity has been shown to be enhanced by SUMOylation.
Gene ID
57459
Gene Name (eCommerce)
GATA zinc finger domain containing 2B
Gene Name (Vector)
GATA zinc finger domain containing 2B
Gene Symbol
GATAD2B
HGNC ID
HGNC:30778
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1782
ORF Size (bp)
1782 bp
Protein Name (eCommerce)
Transcriptional repressor p66-beta
RefSeq ID
NM_020699
RefSeq Synonyms
NM_020699, BC112080, BC112052, BC069419,
Research Areas
Neurobiology,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,neurobiology,transcription_translation
Species
human
Target Sentence
P66beta/GATAD2B interacts with MBD2 (methyl-CpG-binding domain 2) and MBD3 (methyl-CpG-binding domain 3) and participates in transcriptional repression in association with the MBD2/NuRD and MBD3/NuRD histone deacetylase complexes. P66beta/GATAD2B is SUMOylated in vivo and its repressive activity has been shown to be enhanced by SUMOylation.
UniGene ID
Hs.596854
UniProt ID (eCommerce)
Q8WXI9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.