human FZD4 shRNA silencing Adenovirus

Name 
Ad-h-FZD4-shRNA
Cat No 
shADV-209464
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human FZD4.

shADV-209464
Ad-h-FZD4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FZD4 (frizzled class receptor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4
Description (Vector)
FZD4 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Gene ID
8322
Gene Name (Vector)
frizzled class receptor 4
Gene Symbol
FZD4
HGNC ID
HGNC:4042
ORF Size (aa)
1614
ORF Size (bp)
1614 bp
RefSeq ID
NM_012193
RefSeq Synonyms
NM_012193, BC114622, BC114527,
Species
human
UniGene ID
Hs.591968

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.