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human FUT3 shRNA silencing Adenovirus

Name 
Ad-h-FUT3-shRNA
Cat No 
shADV-209421
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human FUT3.

shADV-209421
Ad-h-FUT3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FUT3 (fucosyltransferase 3 (Lewis blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD174; FT3B; FucT-III; LE; Les
Description (Vector)
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Gene ID
2525
Gene Name (Vector)
fucosyltransferase 3 (Lewis blood group)
Gene Symbol
FUT3
HGNC ID
HGNC:4014
ORF Size (aa)
1086
RefSeq ID
NM_000149
RefSeq Synonyms
NM_001097641, NM_001097640, NM_001097639, NM_000149, BC108675, BC074837, BC074836,
Species
human
UniGene ID
Hs.169238

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.