human FOXC2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FOXC2.
shADV-209229
Ad-h-FOXC2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FOXC2 (forkhead box C2 (MFH-1, mesenchyme forkhead 1)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FKHL14; forkhead box C2 (MFH-1, mesenchyme forkhead 1); forkhead box protein C2; forkhead, Drosophila, homolog-like 14; forkhead-related protein FKHL14; LD; mesenchyme fork head protein 1; mesenchyme forkhead 1; MFH1; MFH-1; MFH-1 protein; MFH-1,mesenchyme forkhead 1; transcription factor FKH-14
Description (eCommerce)
FOXC2 (forkhead box protein C2) is a member of the Forkhead transcription factor family. It is critical to the development of lymphatic vasculture. Mutations in FOXC2 are responsible for lymphedema-distichiasis, a disease characterized by the obstruction of lymphatic drainage of the limbs and extra eyelashes (distichiasis).
Description (Vector)
FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
Gene ID
2303
Gene Name (eCommerce)
forkhead box C2
Gene Name (Vector)
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
Gene Symbol
FOXC2
HGNC ID
HGNC:3801
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1506
ORF Size (bp)
1506 bp
Protein Name (eCommerce)
Forkhead box protein C2
RefSeq ID
NM_005251
RefSeq Synonyms
NM_005251, BC113439, BC113437, BC111589,
Research Areas
Cardiac Development,Cardiology,Cardiovascular,Insulin Signaling,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Notch Signaling,Signal Transduction,Transcription Factor/Regulator,VEGF Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
FOXC2 (forkhead box protein C2) is a member of the Forkhead transcription factor family. It is critical to the development of lymphatic vasculture. Mutations in FOXC2 are responsible for lymphedema-distichiasis, a disease characterized by the obstruction of lymphatic drainage of the limbs and extra eyelashes (distichiasis).
UniGene ID
Hs.436448
UniProt ID (eCommerce)
Q99958
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.