human FOLR2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FOLR2.
shADV-209218
Ad-h-FOLR2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FOLR2 (folate receptor beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BETA-HFR; FBP; FBP/PL-1; FR-BETA; FR-P3
Description (Vector)
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Gene ID
2350
Gene Name (Vector)
folate receptor beta
Gene Symbol
FOLR2
HGNC ID
HGNC:3793
ORF Size (aa)
768
ORF Size (bp)
768 bp
RefSeq ID
NM_000803
RefSeq Synonyms
NM_001113536, NM_001113535, NM_001113534, NM_000803, BC058036,
Species
human
UniGene ID
Hs.433159
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.