human FKBP3 shRNA silencing Adenovirus

Name 
Ad-h-FKBP3-shRNA
Cat No 
shADV-209062
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human FKBP3.

shADV-209062
Ad-h-FKBP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FKBP3 (FK506 binding protein 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
25 kDa FK506-binding protein; 25 kDa FKBP; FK506 binding protein 3, 25kDa; FK506-binding protein 25, T-cell; FK506-binding protein 3; FKBP25; FKBP-25; FKBP-3; immunophilin FKBP25; peptidyl-prolyl cis-trans isomerase FKBP3; PPIase; PPIase FKBP3; rapamycin binding protein; rapamycin-selective 25 kDa immunophilin; rotamase
Description (eCommerce)
FK506 binding protein 3 (FKBP3) is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 functions as a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. [taken from NCBI Entrez Gene (GeneID: 2287)].
Description (Vector)
FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Gene ID
2287
Gene Name (eCommerce)
FK506 binding protein 3
Gene Name (Vector)
FK506 binding protein 3
Gene Symbol
FKBP3
HGNC ID
HGNC:3719
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
675
ORF Size (bp)
675 bp
Protein Name (eCommerce)
Peptidyl-prolyl cis-trans isomerase FKBP3
RefSeq ID
NM_002013
RefSeq Synonyms
NM_002013, BC020809, BC016288,
Research Areas
Cancer,Protein Folding
Research Areas (Faceted)
cancer,cell_biology
Species
human
Target Sentence
FK506 binding protein 3 (FKBP3) is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 functions as a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. [taken from NCBI Entrez Gene (GeneID: 2287)].
UniGene ID
Hs.509226
UniProt ID (eCommerce)
Q00688

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.